Human Herpesvirus 8 and Cancer

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[Human herpesvirus 8/Kaposi's sarcoma-associated herpesvirus].

Human herpesvirus 8 (HHV-8), a gammaherpesvirus implicated in Kaposi's sarcoma, primary effusion lymphoma, and Castleman's disease, encodes several pathogenically important cellular homologs. To define the HHV-8 transcription program, RNA obtained from latently infected body cavity-based lymphoma 1 cells induced to undergo lytic replication was used to query a custom HHV-8 DNA microarray contai...

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Multiple human herpesvirus-8 infection.

In Malawian patients with Kaposi sarcoma (KS) and their relatives, we investigated nucleotide-sequence variation in human herpesvirus-8 (HHV-8) subgenomic DNA, amplified from oral and blood samples by use of polymerase chain reaction. Twenty-four people had amplifiable HHV-8 DNA in >1 sample; 9 (38%) were seropositive for human immunodeficiency virus type 1, 21 (88%) were anti-HHV-8-seropositiv...

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Human Herpesvirus 8 Seroprevalence, China

To summarize the seroprevalence of human herpesvirus 8 (HHV-8) in mainland China, we conducted a systematic review and meta-analysis based on available literature. Data show that differences in HHV-8 prevalence vary considerably among different ethnic groups and geographic regions. Blood-borne transmission could be a potential route for HHV-8 infection in China.

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Human Herpesvirus 8, Southern Siberia

1. Calisher CH, Childs JE, Field HE, Holmes KV, Schountz T. Bats: important reservoir hosts of emerging viruses. Clin Microbiol Rev. 2006;19:531–45. DOI: 10.1128/ CMR.00017-06 2. Wong S, Lau S, Woo P, Yuen K-Y. Bats as a continuing source of emerging infections in humans. Rev Med Virol. 2007;17:67– 91. DOI: 10.1002/rmv.520 3. Wibbelt G, Speck S, Field H. Methods for assessing diseases in bats. ...

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Human herpesvirus 8: an update.

The discovery of human herpesvirus 8 (HHV-8) has opened a new field in the biology and in the clinical definition of HHV-8-associated diseases. Various aspects of epidemiology, laboratory diagnosis and treatment of HHV-8 infection are still controversial. This review will summarise the most recent findings on the modalities of viral transmission in geographic areas where the virus is endemic as...

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ژورنال

عنوان ژورنال: JNCI Journal of the National Cancer Institute

سال: 1999

ISSN: 0027-8874,1460-2105

DOI: 10.1093/jnci/91.17.1440